After two bad experiences missing something I really cared about to go to someone's wedding, I have decided that I will never again do that. The only exception would have been my own wedding. And I'm already married.
I gave up a concert ticket once upon a time to go to a relative's wedding. He and his wife did not even send a card when I got married. That one really stung. So...not skipping fun stuff for weddings ever again. If someone was getting married on the Saturday of Nats, the one time I'll ever get to go (unless Omaha gets it again someday), I would have said "have a nice time, I can't make it!"
To be fair, going to your relative's wedding vs. being your best friend's maid of honor aren't quite the same thing....
I'll look forward to hearing all your reports!